Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 18/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 18/20 | 0.46 |
| ▸ | LIPE | Q05469 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779221 | 0.87 | LIPE (0.54) | P2RX3P2RX2LIPE | |
| SCHEMBL2776637 | 0.86 | CCR1 (0.45) | — | |
| SCHEMBL2777291 | 0.84 | EPHX2 (0.53) | LIPE | |
| SCHEMBL2774358 | 0.84 | LIPE (0.59) | LIPE | |
| SCHEMBL2776253 | 0.83 | LIPE (0.45) | LIPE | |
| SCHEMBL2776309 | 0.83 | ACACB (0.46) | — | |
| SCHEMBL2774939 | 0.82 | ACACB (0.44) | — | |
| SCHEMBL2775987 | 0.82 | ACACB (0.42) | — | |
| SCHEMBL2775973 | 0.82 | CCR1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL2774482 | 0.82 | LIPE (0.43) | P2RX3P2RX2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |