Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 7/20 | 0.45 |
| ▸ | CCR1 | P32246 | 6/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778165 | 0.88 | CCR1 (0.48) | CCR1KCNH2HMOX1 | |
| SCHEMBL2774358 | 0.88 | LIPE (0.59) | LIPEHRH3EPHX2ENPP2 | |
| SCHEMBL2777053 | 0.86 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2776334 | 0.86 | HMOX1 (0.53) | CCR1KCNH2HMOX1 | |
| SCHEMBL2776929 | 0.84 | LMNA (0.48) | CCR1KCNH2HMOX1 | |
| SCHEMBL2779821 | 0.84 | CCR1 (0.47) | CCR1EPHX2KCNH2HMOX1 | |
| SCHEMBL2777291 | 0.84 | EPHX2 (0.53) | LIPECCR1EPHX2 | |
| SCHEMBL2773592 | 0.83 | P2RX3 (0.46) | LIPE | |
| SCHEMBL2776114 | 0.82 | ACACB (0.46) | CCR1CYP3A4KCNH2HMOX1 | |
| SCHEMBL2774470 | 0.82 | ACACB (0.44) | CCR1CYP2C9EPHX2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |