Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779821 | 0.85 | CCR1 (0.47) | CCR1KCNH2NAMPTTSHRKMT2A | |
| SCHEMBL2776637 | 0.85 | CCR1 (0.45) | CCR1KCNH2 | |
| SCHEMBL2775860 | 0.85 | CCR1 (0.42) | CCR1KCNH2SRD5A1LMNAALDH1A1 | |
| SCHEMBL2776309 | 0.84 | ACACB (0.46) | CCR1SRD5A1LMNANAMPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2776438 | 0.83 | SRD5A1 (0.46) | SRD5A1NAMPTALDH1A1POLBKMT2A | |
| SCHEMBL2773592 | 0.82 | P2RX3 (0.46) | — | |
| SCHEMBL2779095 | 0.82 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2775987 | 0.82 | ACACB (0.42) | CCR1POLB | |
| SCHEMBL2776784 | 0.82 | CHRM4 (0.45) | LMNANAMPTPOLB | |
| SCHEMBL2777086 | 0.81 | EPHX2 (0.53) | CCR1KCNH2NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |