Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372030 | 0.73 | SMYD3 (0.43) | ALDH1A1MAPK1HIF1AMAPTNPC1 | |
| SCHEMBL5200021 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPK1HIF1AGSK3BMAPT | |
| SCHEMBL9516561 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPK1HIF1AGSK3BLMNA | |
| SCHEMBL27735956 | 0.70 | ALDH1A1 (0.48) | ALDH1A1MAPK1HIF1AGSK3BLMNA | |
| SCHEMBL31210109 | 0.70 | SMYD3 (0.56) | ALDH1A1MAPK1HIF1A | |
| SCHEMBL622063 | 0.70 | SMYD3 (0.56) | ALDH1A1MAPK1HIF1A | |
| SCHEMBL4201093 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPK1HIF1AGSK3BLMNA | |
| SCHEMBL28793214 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MAPK1HIF1AGSK3B | |
| SCHEMBL29481555 | 0.67 | ALDH1A1 (1.00) | ALDH1A1MAPK1HIF1AGSK3BLMNA | |
| SCHEMBL1691536 | 0.67 | ALDH1A1 (1.00) | ALDH1A1MAPK1HIF1AGSK3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410107-A | MIF inhibitors | CORTICAL PTY LTD (AU) | 2009-04-15 | — | — | CN | disclosed |