Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543005 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL4195687 | 0.76 | CMA1 (0.45) | ALDH1A1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL4204225 | 0.75 | PRKAG1 (0.41) | ALDH1A1MAPK1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4197956 | 0.74 | THRB (0.36) | LMNAMAPTSMN1; SMN2GRIA1MEN1 | |
| SCHEMBL640124 | 0.73 | GRIA1 (0.70) | ALDH1A1LMNAMAPTSMN1; SMN2GRIA1 | |
| SCHEMBL27787713 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL4194809 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL9516561 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL27735955 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL8543146 | 0.68 | MAPT (0.40) | ALDH1A1MAPK1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130165-A1 | MIF Inhibitors | CORTICAL PTY LTD | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130165-A1 | MIF Inhibitors | MIF, MMP12, IL4 | ALDH1A1 780/4885MAPK1 940/4885HIF1A 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.