Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427347 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPK1HIF1AHPGDPOLB | |
| SCHEMBL2795538 | 0.83 | GSK3B (0.44) | ALDH1A1MAPK1HIF1AHPGDPOLB | |
| SCHEMBL9227041 | 0.82 | POLB (0.51) | HPGDPOLBAPEX1SMN1; SMN2NPC1 | |
| SCHEMBL3921010 | 0.82 | POLB (0.47) | HPGDPOLBAPEX1SMN1; SMN2NPC1 | |
| SCHEMBL9226589 | 0.80 | POLB (0.50) | ALDH1A1HPGDPOLBAPEX1SMN1; SMN2 | |
| SCHEMBL9275403 | 0.79 | POLB (0.49) | ALDH1A1MAPK1HPGDPOLBAPEX1 | |
| SCHEMBL8055152 | 0.78 | POLB (0.55) | HPGDPOLBAPEX1SMN1; SMN2NPC1 | |
| SCHEMBL488780 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1HIF1AHPGDSMN1; SMN2 | |
| SCHEMBL5704428 | 0.76 | GSK3B (0.43) | ALDH1A1MAPK1HIF1AHPGDPOLB | |
| SCHEMBL9186659 | 0.76 | GAA (0.56) | ALDH1A1HPGDPOLBAPEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411252-B1 | Process for the preparation of fluorobenzoic acids | RIEDEL DE HAEN AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-5093529-A | Process for the preparation of fluorinated benzoic acids | CASSELLA AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0411252-A1 | Process for the preparation of fluorobenzoic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1991-02-06 | — | — | EP | disclosed |