Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.65 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | ST6GAL1 | P15907 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612107 | 0.89 | LMNA (0.65) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL331768 | 0.87 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL30608768 | 0.87 | LMNA (0.74) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL22387116 | 0.86 | P2RY6 (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL6060610 | 0.86 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL15798740 | 0.86 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL16555170 | 0.86 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL236108 | 0.86 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| Trifluoroacetic Acid SCHEMBL4666697 | 0.85 | LMNA (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL11852751 | 0.85 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101252839-A | Novel 2 '-C-methyl and 4' -C-methyl nucleoside derivatives | MERCK & CO INC (US) | 2008-08-27 | — | — | CN | disclosed |