Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.61 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.61 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | CPN1 | P15169 | 2/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793461 | 0.87 | — | — | |
| SCHEMBL14206645 | 0.83 | TSHR (0.46) | SLC6A1SLC6A11SLC6A13TSHRLMNA | |
| SCHEMBL28099042 | 0.83 | TSHR (0.46) | SLC6A1SLC6A11SLC6A13TSHRLMNA | |
| SCHEMBL4772461 | 0.78 | SLC6A1 (0.71) | SLC6A1SLC6A11SLC6A13TSHRLMNA | |
| Nipecotic Acid SCHEMBL456856 | 0.76 | SLC6A1 (1.00) | SLC6A1SLC6A11SLC6A13TSHRLMNA | |
| (R)-Nipecotic Acid SCHEMBL29880539 | 0.76 | — | — | |
| (R)-Nipecotic Acid SCHEMBL520075 | 0.76 | — | — | |
| Nipecotic Acid SCHEMBL85677 | 0.76 | — | — | |
| (S)-Nipecotic Acid SCHEMBL254683 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27891040 | 0.76 | SLC6A1 (0.68) | SLC6A1SLC6A11SLC6A13TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020874-A | A kind of Eliquis intermediate and preparation method thereof | 上海雅本化学有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-107108871-A | The manufacture method of polyester | 日本曹达株式会社 | 2017-08-29 | — | — | CN | claimed |
| CN-110016020-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109384778-A | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 铁木医药有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-109369635-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-108947985-A | Compound and its preparation method and application as autophagy regulator | 苏州偶领生物医药有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108912111-A | compounds and pharmaceutical compositions | 铁木医药有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-105408328-B | sGC stimulators | 铁木医药有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-106278968-B | A kind of method for synthesizing sulfo-amino acid derivative | 华东理工大学 | 2018-02-13 | — | — | CN | disclosed |
| CN-104817561-B | The Piperidine inhibitors of JAK3 | 奥斯拜客斯制药有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106278968-A | A kind of method synthesizing sulfo-amino acid derivative | 华东理工大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-105408328-A | sGC stimulators | IRONWOOD PHARMACEUTICALS INC | 2016-03-16 | — | — | CN | disclosed |
| CN-104817561-A | Piperidine inhibitors of Janus Kinase 3 | AUSPEX PHARMACEUTICALS LLC | 2015-08-05 | — | — | CN | disclosed |
| CN-102459270-B | Piperidine inhibitors of janus kinase 3 | AUSPEX PHARMACEUTICALS LLC | 2015-04-29 | — | — | CN | disclosed |
| CN-103347873-A | Pyrazole derivative and pest control agent | NISSAN CHEMICAL IND LTD | 2013-10-09 | — | — | CN | disclosed |
| CN-101243087-B | 1,4-dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them | AVENTIS PHARMA SA | 2013-07-24 | — | — | CN | disclosed |
| CN-101243087-A | 1,4-dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them | AVENTIS PHARMA SA (FR) | 2008-08-13 | — | — | CN | disclosed |