Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793896 | 0.83 | RORC (0.56) | RORCPTGER1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4772011 | 0.81 | RORC (0.49) | RORCALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27736728 | 0.80 | PTGER1 (0.46) | PTGER1ALDH1A1MAPTRECQLSCN9A | |
| SCHEMBL27715915 | 0.80 | RORC (0.46) | RORCRECQLSCN9ACYP3A4CYP2C9 | |
| SCHEMBL4792570 | 0.79 | RORC (0.60) | RORCCYP3A4CYP2C9 | |
| SCHEMBL4768485 | 0.75 | RORC (0.55) | RORCALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL4768479 | 0.75 | RORC (0.55) | RORCALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL25016679 | 0.74 | OPRK1 (0.51) | ALOX5APOPRK1 | |
| SCHEMBL11837155 | 0.73 | KMT2A (0.54) | PTGER1ALDH1A1MAPTRECQLSCN9A | |
| SCHEMBL13430729 | 0.72 | PTGER1 (0.50) | RORCPTGER1ALDH1A1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268048-A | Carbazole derivatives | SERENEX INC (US) | 2008-09-17 | — | — | CN | disclosed |