Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837155 | 0.89 | KMT2A (0.54) | PTGER1KMT2ASCN9AALDH1A1MAPT | |
| SCHEMBL27736730 | 0.80 | RORC (0.47) | PTGER1PTGER3TBXA2RSCN9AALDH1A1 | |
| SCHEMBL27715919 | 0.79 | HTR7 (0.48) | PTGER1KMT2ASCN9AALDH1A1MAPT | |
| SCHEMBL13430729 | 0.78 | PTGER1 (0.50) | PTGER1KMT2APTGER3SCN9AALDH1A1 | |
| SCHEMBL11830442 | 0.77 | HTR7 (0.43) | ALDH1A1MAPTRECQLHTR7 | |
| SCHEMBL13430734 | 0.76 | PTGER1 (0.55) | PTGER1KMT2APTGER3SCN9AHTR7 | |
| SCHEMBL11838800 | 0.75 | GAA (0.38) | ALDH1A1MAPTRECQLCYP19A1HTR7 | |
| SCHEMBL11838806 | 0.75 | GAA (0.38) | ALDH1A1MAPTRECQLCYP19A1HTR7 | |
| SCHEMBL23586493 | 0.74 | KMT2A (0.50) | PTGER1KMT2AALDH1A1MAPTRECQL | |
| SCHEMBL31116748 | 0.74 | RORC (0.42) | KMT2ASCN9AALDH1A1MAPTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268048-A | Carbazole derivatives | SERENEX INC (US) | 2008-09-17 | — | — | CN | disclosed |