SCHEMBL2773687

SCHEMBL2773687

C=Cc1ccccc1[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2773561 1.00 ALDH1A1 (0.32) ALDH1A1
SCHEMBL373727 0.98 ALDH1A1 (0.33) ALDH1A1
SCHEMBL372504 0.98 ALDH1A1 (0.33) ALDH1A1
SCHEMBL373084 0.97 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373429 0.92 ALDH1A1 (0.38) ALDH1A1
SCHEMBL30862129 0.92 ALDH1A1 (0.38) ALDH1A1
SCHEMBL374949 0.83 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373779 0.83 ALDH1A1 (0.34) ALDH1A1
SCHEMBL5701390 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL441041 0.78 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770888-B1 Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production MENICON CO LTD (JP) 2004-08-04 EP claimed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
EP-2453292-B1 SOFT HYBRID CONTACT LENS, METHOD FOR PRODUCING SAME, AND HYDRATION METHOD MENICON CO LTD (JP) 2016-09-07 EP disclosed
US-8662663-B2 Hybrid soft contact lens, and production method and hydration treatment method thereof MENICON CO., LTD. (JP) 2014-03-04 US disclosed
US-20120169994-A1 HYBRID SOFT CONTACT LENS, AND PRODUCTION METHOD AND HYDRATION TREATMENT METHOD THEREOF MENICON CO., LTD. (JP) 2012-07-05 US disclosed
EP-2453292-A1 SOFT HYBRID CONTACT LENS, METHOD FOR PRODUCING SAME, AND HYDRATION METHOD Menicon Co., Ltd. (JP) 2012-05-16 EP disclosed
EP-1750157-B1 CONTACT LENS MENICON CO LTD (JP) 2010-10-13 EP disclosed
EP-2174966-A1 OPTICAL MATERIAL AND OPHTHALMIC LENS MADE OF THE SAME Menicon Co., Ltd. (JP) 2010-04-14 EP disclosed
US-7588334-B2 Contact lens MENICON CO., LTD. (JP) 2009-09-15 US disclosed
EP-1033590-B1 Ocular lens material MENICON CO LTD (JP) 2008-05-07 EP disclosed
US-20070232755-A1 Contact Lens MENICON CO., LTD. (JP) 2007-10-04 US disclosed
EP-0381005-B1 Ocular lens material MENICON CO LTD (JP) 1995-01-11 EP disclosed
US-5346946-A Polysiloxane macromonomer MENICON CO., LTD (JP) 1994-09-13 US disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0578087-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-01-12 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
EP-0381005-A2 Ocular lens material Menicon Co., Ltd. (JP) 1990-08-08 EP disclosed
US-4594401-A Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-06-10 US disclosed