SCHEMBL372504

SCHEMBL372504

C=Cc1ccccc1[Si](O[Si](C)(C)C)(O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373727 1.00 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2773687 0.98 ALDH1A1 (0.32) ALDH1A1
SCHEMBL2773561 0.98 ALDH1A1 (0.32) ALDH1A1
SCHEMBL373084 0.98 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373429 0.93 ALDH1A1 (0.38) ALDH1A1
SCHEMBL30862129 0.93 ALDH1A1 (0.38) ALDH1A1
SCHEMBL374949 0.85 ALDH1A1 (0.34) ALDH1A1
SCHEMBL373779 0.85 ALDH1A1 (0.34) ALDH1A1
SCHEMBL5701390 0.79 ALDH1A1 (0.35) ALDH1A1
SCHEMBL441041 0.79 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
US-12428390-B2 Chromene compound and photochromic optical article TOKUYAMA CORPORATION (JP) 2025-09-30 US disclosed
EP-3822296-B1 POLYMER MATERIAL MENICON CO LTD (JP) 2025-09-10 EP disclosed
WO-2025094241-A1 COMPOSITE MEMBRANE 株式会社メニコン 2025-05-08 WO disclosed
US-20250115701-A1 POLYMER MATERIAL MENICON CO., LTD. (JP) 2025-04-10 US disclosed
US-12209154-B2 Polymer material MENICON CO., LTD. (JP) 2025-01-28 US disclosed
EP-3995493-B1 CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE TOKUYAMA CORP (JP) 2024-07-03 EP disclosed
US-20240026145-A1 OPHTHALMIC LENS MENICON CO., LTD. (JP) 2024-01-25 US disclosed
EP-4206797-A1 OPHTHALMIC LENS Menicon Co., Ltd. (JP) 2023-07-05 EP disclosed
EP-2657304-B1 AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS MENICON CO LTD (JP) 2022-12-07 EP disclosed
EP-1134071-A2 Process for preparing ultraviolet-ray-absorbable and low water-containing soft contact lens Menicon Co., Ltd. (JP) 2001-09-19 EP disclosed
EP-0989138-A2 Ocular lens material and process for producing the same Menicon Co., Ltd. (JP) 2000-03-29 EP disclosed
US-6018001-A ACID TREATMENT OF A CONTACT LENS WHICH IS A COPOLYMER OF ASUGAR KETAL-CONTAINING (METH)ACRYLATE AND A SUGAR GLYCEROL KETAL-CONTAINING (METH)ACRYLATE AND A CO-MONOMER CONTAINING SILICON AND FLUORINE-MONOMER; OXYGEN PERMEABILITY MENICON CO., LTD. (JP) 2000-01-25 US disclosed
EP-0892297-A1 PROCESS FOR PRODUCING CONTACT LENS WITH HYDROPHILIC SURFACE AND CONTACT LENS OBTAINED THEREBY MENICON CO., LTD. (JP) 1999-01-20 EP disclosed
EP-0890636-A1 Culture vessel Menicon Co., Ltd. (JP) 1999-01-13 EP disclosed
US-5741830-A COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE MENICON CO., LTD. (JP) 1998-04-21 US disclosed
EP-0796723-A1 PROCESS FOR PRODUCING OPTIC LENS AND OPTIC LENS OBTAINED THEREBY MENICON CO., LTD. (JP) 1997-09-24 EP disclosed
EP-0729041-A2 Water-Absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-08-28 EP disclosed
US-5416180-A Fluorine containing (meth)acrylate polymers MENICON CO., LTD. (JP) 1995-05-16 US disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428390-B2 Chromene compound and photochromic optical article CRY1, CRY2, RAD51 ALDH1A1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.