SCHEMBL27736952

SCHEMBL27736952

CCCC1=Cc2c(-c3ccc(CC)cc3)cccc2C1[Zr]

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
PTAFR P25105 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27757804 0.92 EDNRB (0.33) EDNRBEDNRAPTAFR
SCHEMBL27687651 0.90 EDNRB (0.36) EDNRBEDNRAPTAFR
SCHEMBL27757688 0.90 SLC6A2 (0.34) EDNRBEDNRA
SCHEMBL27757731 0.90 HSD11B1 (0.35)
SCHEMBL27736995 0.89 CRHR1 (0.33) EDNRBEDNRA
SCHEMBL27463589 0.87 ADRB2 (0.33)
SCHEMBL27757729 0.87 HSD17B10 (0.38)
SCHEMBL28779214 0.87 HSD11B1 (0.33)
SCHEMBL27757807 0.85 HSD11B1 (0.36)
Hydrochloric Acid SCHEMBL28035007 0.85 ADRB2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101356199-A Method for producing ultra-high molecular weight polymers by means of special bridged metallocene catalysts TICONA GMBH (DE) 2009-01-28 CN disclosed