Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545527 | 0.76 | TTK (0.48) | ALDH1A1KDM4EHPGDTTKAKR1B1 | |
| SCHEMBL27760614 | 0.75 | HDAC3 (0.49) | MEN1LMNAHTTKMT2ACHRM2 | |
| SCHEMBL2299132 | 0.75 | KIF11 (0.44) | ALDH1A1KDM4EMEN1KMT2ATTK | |
| SCHEMBL8239566 | 0.72 | SLC6A2 (0.46) | ALDH1A1TTKCHRM2CHRM1MAPT | |
| SCHEMBL4636341 | 0.72 | HTR6 (0.52) | TTKHTR2CHTR6 | |
| SCHEMBL3535448 | 0.72 | HTR6 (0.45) | ALDH1A1HTTTTKMAPTHTR6 | |
| SCHEMBL3531911 | 0.72 | HTR6 (0.44) | LMNATTKITKDRD2HTR2C | |
| SCHEMBL3530040 | 0.72 | TTK (0.42) | ALDH1A1KDM4ETTK | |
| SCHEMBL3948503 | 0.71 | HTR6 (0.52) | ALDH1A1LMNAHPGDTSHRMAPT | |
| SCHEMBL3948910 | 0.71 | HTR6 (0.67) | DRD2HTR2CHTR7HTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282938-A | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2008-10-08 | — | — | CN | disclosed |