Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | AGER | Q15109 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717297 | 0.87 | SMN1; SMN2 (0.39) | RAB9AHDAC8SMN1; SMN2L3MBTL1CNR1 | |
| SCHEMBL27717298 | 0.85 | ALOX15 (0.34) | HDAC8ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3676906 | 0.74 | NPC1 (0.36) | NPC1RAB9APOLBHDAC8ALDH1A1 | |
| SCHEMBL27738344 | 0.73 | CDK9 (0.36) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11964465 | 0.64 | MAPT (0.59) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL31720822 | 0.64 | MAPT (0.59) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL3673565 | 0.64 | NPC1 (0.37) | NPC1RAB9APOLBHDAC8ALDH1A1 | |
| SCHEMBL27738345 | 0.62 | ALDH1A1 (0.35) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11901731 | 0.61 | MAPT (0.56) | POLBALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30936578 | 0.61 | MAPT (0.56) | POLBALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102558245-A | Catalyst composition comprising group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEMICAL LTD | 2012-07-11 | — | — | CN | disclosed |
| CN-101300261-A | Catalyst composition comprising group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEMICAL LTD (KR) | 2008-11-05 | — | — | CN | disclosed |
| CN-101296932-A | Transition metal complex and preparation method thereof | LG CHEMICAL LTD (KR) | 2008-10-29 | — | — | CN | disclosed |