Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.35 |
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561546 | 0.88 | ALDH1A1 (0.53) | ALDH1A1RXFP1NUDT1MEN1KMT2A | |
| SCHEMBL237122 | 0.88 | ALDH1A1 (0.53) | ALDH1A1RXFP1NUDT1MEN1KMT2A | |
| SCHEMBL30175417 | 0.83 | ALDH1A1 (0.46) | ALDH1A1RXFP1NUDT1MEN1KMT2A | |
| SCHEMBL383842 | 0.80 | ALDH1A1 (0.43) | ALDH1A1RXFP1 | |
| 2-Aminopurine SCHEMBL2776661 | 0.77 | ALDH1A1 (0.77) | ALDH1A1RXFP1KDM4EPNPCYP1A2 | |
| SCHEMBL4283927 | 0.75 | ALDH1A1 (0.42) | ALDH1A1RXFP1NUDT1MEN1KMT2A | |
| SCHEMBL28746716 | 0.75 | ALDH1A1 (0.34) | ALDH1A1RXFP1NUDT1HSD17B10AKR1B1 | |
| SCHEMBL27657809 | 0.73 | ALDH1A1 (0.50) | ALDH1A1RXFP1NUDT1KMT2A | |
| 2-Aminopurine SCHEMBL20305132 | 0.71 | ALDH1A1 (0.79) | ALDH1A1RXFP1KDM4EPNPCYP1A2 | |
| Thymine SCHEMBL3100655 | 0.71 | ATAD2 (0.50) | ALDH1A1RXFP1NUDT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790877-B2 | Antisense oligonucleotides with increased RNase sensitivity | GEN-PROBE, INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1019539-A4 | COMBINATORIAL ANTISENSE LIBRARY | GEN PROBE INC (US) | 2005-03-09 | — | — | EP | disclosed |
| EP-1019539-A1 | COMBINATORIAL ANTISENSE LIBRARY | Oasis Biosciences, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999018238-A1 | COMBINATORIAL ANTISENSE LIBRARY | OASIS BIOSCIENCES, INC. (US) | 1999-04-15 | — | — | WO | disclosed |