Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 14/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692989 | 0.76 | GABRP (0.33) | KMT2AALDH1A1MEN1 | |
| SCHEMBL1531229 | 0.69 | ALDH1A1 (0.35) | KDM4ETDP1KMT2ALMNAALDH1A1 | |
| SCHEMBL61992 | 0.67 | ALDH1A1 (0.44) | TDP1KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL19204875 | 0.66 | — | — | |
| SCHEMBL4922723 | 0.64 | ALDH1A1 (0.38) | TDP1ALDH1A1 | |
| SCHEMBL22529462 | 0.63 | — | — | |
| SCHEMBL447325 | 0.63 | — | — | |
| SCHEMBL4925952 | 0.61 | ALDH1A1 (0.33) | LMNAALDH1A1 | |
| SCHEMBL29389721 | 0.61 | PIN1 (0.53) | PIN1 | |
| SCHEMBL27708875 | 0.61 | ALDH1A1 (0.39) | TDP1KMT2ALMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101917995-A | POLO-like kinase inhibitors | TAKEDA PHARMACEUTICAL | 2010-12-15 | — | — | CN | disclosed |
| CN-101448830-A | Dihydropteridine compounds as anti proliferative agents | ASTRAZENECA AB (SE) | 2009-06-03 | — | — | CN | disclosed |