Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346725 | 0.83 | HTT (0.66) | HTTLMNAMAPK1RAB9AHRH3 | |
| SCHEMBL9263449 | 0.76 | ALDH1A1 (0.57) | HTTRAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL19287206 | 0.72 | HTT (0.59) | HTTLMNAMAPK1RAB9AHRH3 | |
| SCHEMBL4495664 | 0.71 | HTT (0.68) | HTTLMNAMAPK1RAB9AHRH3 | |
| SCHEMBL6580881 | 0.71 | HTT (0.63) | HTTLMNAMAPK1RAB9AHRH3 | |
| SCHEMBL5729116 | 0.71 | RAB9A (0.63) | HTTLMNAMAPK1RAB9AHRH3 | |
| SCHEMBL11743831 | 0.71 | USP5 (0.49) | LMNARAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL5313540 | 0.71 | USP5 (0.49) | LMNARAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL1527427 | 0.71 | CTNNB1 (0.73) | HRH3ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL29923058 | 0.71 | CTNNB1 (0.73) | HRH3ALDH1A1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421392-A | Use of indanoyl amide to stimulate secondary metabolism in taxus sp | PHYTON BIOTECH INC (US) | 2009-04-29 | — | — | CN | disclosed |