Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.38 |
| ▸ | EIF4E | P06730 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23790873 | 0.84 | GFER (0.59) | TP53GFERMAPTPOLBLMNA | |
| SCHEMBL4906170 | 0.82 | GFER (0.48) | TP53GFERMAPTPOLBLMNA | |
| SCHEMBL27720184 | 0.82 | LMNA (0.52) | TP53MAPTPOLBLMNARXFP1 | |
| SCHEMBL4904228 | 0.81 | TP53 (0.49) | TP53GFERMAPTPOLBLMNA | |
| SCHEMBL3371711 | 0.79 | GFER (0.67) | TP53GFERMAPTPOLBLMNA | |
| SCHEMBL16398876 | 0.78 | GFER (0.49) | TP53GFERMAPTPOLBLMNA | |
| SCHEMBL14270279 | 0.76 | LMNA (0.50) | MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL27740960 | 0.76 | LMNA (0.50) | TP53MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL19031369 | 0.72 | GFER (0.60) | TP53GFERMAPTPOLBLMNA | |
| SCHEMBL2662446 | 0.70 | ABL1 (0.46) | POLBEIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287718-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2008-10-15 | — | — | CN | disclosed |