Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 14/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720184 | 0.85 | LMNA (0.52) | LMNAMAPTKDM4ETP53POLB | |
| SCHEMBL23790873 | 0.82 | GFER (0.59) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL14270279 | 0.82 | LMNA (0.50) | LMNAMAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL27720173 | 0.80 | LMNA (0.56) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL27912402 | 0.79 | LMNA (0.55) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL3370362 | 0.79 | LMNA (0.58) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL4905756 | 0.79 | LMNA (0.55) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL6343767 | 0.79 | LMNA (0.55) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL4907133 | 0.77 | LMNA (0.56) | LMNAMAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL4903824 | 0.77 | LMNA (0.53) | LMNAMAPTKDM4ESMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287718-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2008-10-15 | — | — | CN | disclosed |