Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19031520 | 0.87 | LMNA (0.54) | LMNAALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL23790873 | 0.86 | GFER (0.59) | LMNAALDH1A1MAPTPOLBTP53 | |
| SCHEMBL14270279 | 0.85 | LMNA (0.50) | LMNAALDH1A1HPGDMAPTPOLB | |
| SCHEMBL27740960 | 0.85 | LMNA (0.50) | LMNAMAPTPOLBTP53KDM4E | |
| SCHEMBL27740965 | 0.82 | TP53 (0.43) | LMNAL3MBTL1MAPTPOLBTP53 | |
| SCHEMBL4902662 | 0.77 | LMNA (0.63) | LMNAALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL2228478 | 0.77 | LMNA (0.59) | LMNAALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL31163793 | 0.77 | LMNA (0.59) | LMNAALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL201736 | 0.73 | GFER (0.72) | LMNAALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL2225013 | 0.73 | LMNA (0.62) | LMNAALDH1A1HPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287718-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2008-10-15 | — | — | CN | disclosed |