Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742489 | 0.82 | PREP (0.41) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL4182936 | 0.82 | CA12 (0.36) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL4187296 | 0.80 | DRD2 (0.43) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL27742545 | 0.76 | TYR (0.41) | CA12CA1CA9SLC18A3ALDH1A1 | |
| SCHEMBL15876126 | 0.76 | CA12 (0.39) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL27721793 | 0.76 | PPARA (0.39) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL19696788 | 0.75 | CNR2 (0.41) | GAAALDH1A1CNR2 | |
| SCHEMBL6434340 | 0.71 | CA12 (0.39) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL6435288 | 0.71 | MTNR1A (0.37) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL6433452 | 0.71 | MTNR1A (0.37) | PREPCA12CA1CA9HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101304993-A | Compounds and compositions as ppar modulators | IRM LLC (BM) | 2008-11-12 | — | — | CN | disclosed |