SCHEMBL27743370

SCHEMBL27743370

CC(=S)CC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.31
BRD4 O60885 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
MGLL Q99685 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6033533 0.85 MGAM (0.43) GLABRD4ADORA3ADORA2AADORA2B
SCHEMBL2618714 0.84 MGLL (0.34) BRD4ADORA3ADORA2AADORA2BMGLL
SCHEMBL13183261 0.81 BRD4 (0.39) GLABRD4MGLL
SCHEMBL19196318 0.79 KMT2A (0.34) MGLL
SCHEMBL13286870 0.78 PLK1 (0.32) BRD4ADORA3ADORA2AADORA2BMGLL
SCHEMBL142707 0.78 MGAM (0.31) GLAMGLL
SCHEMBL14769218 0.77 TSHR (0.36) MGLL
SCHEMBL18350690 0.76 ATM (0.35)
SCHEMBL13445908 0.76 SLC1A2 (0.32) GLAMGLL
SCHEMBL2615822 0.76 NPSR1 (0.34) GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101448854-A Fusion protein comprising an Fc receptor binding polypeptide and an antigenic polypeptide for mediating an immune response IMMUNOBIOLOGY LTD (GB) 2009-06-03 CN disclosed