SCHEMBL142707

SCHEMBL142707

CC(=O)CC(=S)ON1C(=O)CCC1=O

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
GLA P06280 1/20 0.31
TLR4 O00206 3/20 0.30
MGLL Q99685 4/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733349 0.84 ALDH1A1 (0.36) GLAALDH1A1
SCHEMBL6033533 0.81 MGAM (0.43) MGAMGAASIMGAM2GLA
SCHEMBL28965160 0.81 PAOX (0.31)
SCHEMBL27743370 0.78 GLA (0.31) GLAMGLL
SCHEMBL4618888 0.76 GLA (0.32) GLAMGLL
SCHEMBL9724338 0.74 SMN1; SMN2 (0.47) MGLLALDH1A1MAPT
SCHEMBL30779753 0.73 GLA (0.41) GLAMGLLALDH1A1
SCHEMBL30699 0.73 GLA (0.41) GLAMGLLALDH1A1
SCHEMBL18510166 0.73 GLA (0.41) GLAMGLLALDH1A1
SCHEMBL28381750 0.73 PSMB8 (0.33) GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996942-A Macrophage-targeting peptides, conjugates, compositions and uses thereof 双亥生命科学株式会社 2023-04-21 CN claimed
EP-4103585-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF Twinpig Biolab, Inc. (KR) 2022-12-21 EP claimed
US-20220354957-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 US claimed
WO-2022234346-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 WO claimed
US-11484601-B2 Targeting M2-like tumor-associated macrophages by using melittin-based proapoptotic peptide TWINPIGBIOLAB INC. (KR) 2022-11-01 US claimed
US-20210244823-A1 TARGETING M2-LIKE TUMOR-ASSOCIATED MACROPHAGES BY USING MELITTIN-BASED PROAPOPTOTIC PEPTIDE TWINPIGBIOLAB INC. (KR) 2021-08-12 US claimed
EP-3789041-A1 TARGETING M2-LIKE TUMOR-ASSOCIATED MACROPHAGES BY USING MELITTIN-BASED PRO-APOPTOTIC PEPTIDE Twinpigbiolab Inc. (KR) 2021-03-10 EP claimed
US-10605810-B2 Pincers comprising antibody and aptamer conjugated via a linker which binds to the same target material and use thereof UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2020-03-31 US claimed
EP-2906607-A2 POLYMERS HAVING ORTHOGONAL REACTIVE GROUPS AND USES THEREOF NVS Technologies Inc. (US) 2015-08-19 EP claimed
EP-2478049-B1 A POLYMER SUPPORT UNIV CAPE TOWN (ZA) 2015-02-25 EP claimed
WO-2007046865-A1 BIOLOGICAL INDICATOR STERIS, INC. (US) 2007-04-26 WO claimed
US-20060269983-A1 Biological indicator AMERICAN STERILIZER COMPANY 2006-11-30 US claimed
WO-2006109311-A2 ENZYME-CHANNELING BASED ELECTROCHEMICAL BIOSENSORS RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-10-19 WO claimed
WO-2006069366-A1 METHODS OF PROTEIN PROFILING BY THIOLATION INTEL CORPORATION (US) 2006-06-29 WO claimed
US-20060134694-A1 Methods of protein profiling by thiolation INTEL CORPORATION (US) 2006-06-22 US claimed
EP-1506399-A2 METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS Aclara BioSciences, Inc. (US) 2005-02-16 EP claimed
US-20030013126-A1 Methods and compositions for analyzing proteins MONOGRAM BIOSCIENCES, INC. 2003-01-16 US claimed
US-20020197649-A1 Catalytic amplification of multiplexed assay signals MONOGRAM BIOSCIENCES, INC. 2002-12-26 US claimed
WO-2002097112-A2 CATALYTIC AMPLIFICATION OF MULTIPLEXED ASSAY SIGNALS ACLARA BIOSCIENCES, INC. (US) 2002-12-05 WO claimed
WO-2002095356-A2 METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS ACLARA BIOSCIENCES, INC. (US) 2002-11-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10605810-B2 Pincers comprising antibody and aptamer conjugated via a linker which binds to the same target material and use thereof ILK, PAICS, AURKC MGAM 3401/4885GAA 1675/4885SI 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.