Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | FHIT | P49789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25475531 | 0.89 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL29201220 | 0.84 | ALDH1A1 (0.55) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL25379723 | 0.84 | ALDH1A1 (0.55) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL25380338 | 0.84 | ALDH1A1 (0.55) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL31581362 | 0.84 | ALDH1A1 (0.55) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL29153995 | 0.84 | ALDH1A1 (0.55) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL25380339 | 0.84 | ALDH1A1 (0.55) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL19678522 | 0.83 | ALDH1A1 (0.47) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL27702993 | 0.79 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDSMN1; SMN2MAPT | |
| SCHEMBL27534697 | 0.79 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100432071-C | Substituted 1H-indole-2-ketone compound and its preparation method and uses | SHANGHAI INST MATERIA MEDICA (CN) | 2008-11-12 | — | — | CN | disclosed |