SCHEMBL19678522

SCHEMBL19678522

CCOC(=O)c1c(I)c(I)c(I)c(I)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.47
▸ USP2 O75604 1/20 0.46
▸ HPGD P15428 5/20 0.46
▸ SMN1; SMN2 Q16637 4/20 0.46
▸ GAA P10253 4/20 0.46
▸ MAPT P10636 4/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA7 P43166 1/20 0.46
▸ CA9 Q16790 1/20 0.46
▸ CA14 Q9ULX7 1/20 0.46
▸ NR1H2 P55055 1/20 0.44
▸ NR1H3 Q13133 1/20 0.44
▸ PDE4D Q08499 1/20 0.43
▸ FHIT P49789 1/20 0.42
▸ KMT2A Q03164 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27744428 0.83 ALDH1A1 (0.47) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL25475531 0.82 ALDH1A1 (0.50) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL25380339 0.81 ALDH1A1 (0.55) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL29153995 0.81 ALDH1A1 (0.55) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL31581362 0.81 ALDH1A1 (0.55) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL25380338 0.81 ALDH1A1 (0.55) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL29201220 0.81 ALDH1A1 (0.55) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL25379723 0.81 ALDH1A1 (0.55) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL30017866 0.78 NR1H2 (0.47) ALDH1A1USP2HPGDSMN1; SMN2GAA
SCHEMBL19678523 0.77 CA12 (0.40) ALDH1A1HPGDSMN1; SMN2MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 — — US disclosed
US-20230273519-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMATION METHOD JSR CORPORATION (JP) 2023-08-31 — — US disclosed
US-20220026803-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-01-27 — — US disclosed
US-11204553-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-21 — — US disclosed
US-20200241418-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 — — US disclosed
US-20200050104-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 — — US disclosed
US-10295904-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-05-21 — — US disclosed
US-20180088463-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 — — US disclosed
US-20180081267-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-22 — — US disclosed
US-20180081267-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-22 — — US disclosed
US-20170351177-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-07 — — US disclosed
US-20170351177-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170351177-A1 RESIST COMPOSITION AND PATTERNING PROCESS INSR, EWSR1, INSRR ALDH1A1 4870/4885USP2 2830/4885HPGD 4484/4885
US-10295904-B2 Resist composition and patterning process INSR, EWSR1, INSRR ALDH1A1 4870/4885USP2 2830/4885HPGD 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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