Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044033 | 0.83 | CHRM2 (0.33) | MAPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL4017978 | 0.80 | DPP4 (0.41) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL21673908 | 0.80 | DPP4 (0.41) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL31301933 | 0.80 | CYP1A2 (0.42) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL695946 | 0.80 | DPP4 (0.41) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL29308166 | 0.80 | MAPK1 (0.36) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL12531141 | 0.80 | MAPK1 (0.36) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL19901590 | 0.80 | CYP1A2 (0.42) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL29308170 | 0.80 | DPP4 (0.41) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL28146362 | 0.80 | DPP4 (0.41) | MAPK1L3MBTL1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466726-B | Azacyclo derivatives of androstanes and androstenes as medicaments for the treatment of cardiovascular disorders | SIGMA TAU IND FARMACEUTI | 2014-09-24 | — | — | CN | disclosed |
| CN-101466726-A | Azacyclo derivatives of androstanes and androstenes as medicaments for the treatment of cardiovascular disorders | SIGMA TAU IND FARMACEUTI (IT) | 2009-06-24 | — | — | CN | disclosed |