Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359958 | 0.84 | MAPK1 (0.36) | CHRM2CHRM1CHRM3HRH3MAPK1 | |
| SCHEMBL22152561 | 0.84 | MAPK1 (0.36) | CHRM2CHRM1CHRM3HRH3MAPK1 | |
| SCHEMBL7379626 | 0.84 | MAPK1 (0.36) | CHRM2CHRM1CHRM3HRH3MAPK1 | |
| SCHEMBL27744679 | 0.83 | MAPK1 (0.32) | CHRM2CHRM1CHRM3MAPK1 | |
| SCHEMBL5261052 | 0.81 | CHRM2 (0.40) | CHRM2CHRM1CHRM3HRH3MAPK1 | |
| SCHEMBL7512909 | 0.78 | L3MBTL1 (0.34) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6527936 | 0.78 | CHRNB2 (0.38) | CHRM2CHRM1CHRM3HRH3 | |
| SCHEMBL27682940 | 0.78 | NR1H2 (0.41) | — | |
| SCHEMBL6519626 | 0.78 | CHRNB2 (0.38) | CHRM2CHRM1CHRM3HRH3 | |
| SCHEMBL8506360 | 0.76 | HRH3 (0.34) | CHRM2CHRM1CHRM3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189479-A | Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds | SUZHOU ZELGEN BIOPHARMACEUTICALS CO LTD | 2015-12-23 | — | — | CN | disclosed |