Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.31 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780820 | 0.85 | EGLN1 (0.35) | EGLN1RORCPPARGPPARAMMP8 | |
| SCHEMBL27744659 | 0.84 | SLC6A9 (0.41) | RORCMMP8MMP3MMP2 | |
| SCHEMBL1471107 | 0.81 | EGLN1 (0.49) | EGLN1MMP3HDAC6MMP2 | |
| SCHEMBL27765610 | 0.80 | SLC6A9 (0.38) | RORC | |
| SCHEMBL27765715 | 0.79 | F13A1 (0.44) | — | |
| SCHEMBL27744707 | 0.77 | NOTUM (0.36) | RORCMMP2 | |
| SCHEMBL27744761 | 0.76 | F13A1 (0.34) | RORC | |
| SCHEMBL27765691 | 0.75 | NOTUM (0.36) | RORC | |
| SCHEMBL27744683 | 0.75 | RORC (0.35) | RORC | |
| SCHEMBL27744699 | 0.74 | NOTUM (0.44) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421258-B | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYPSYS INC | 2013-08-21 | — | — | CN | disclosed |
| CN-101421258-A | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYSPSYS INC (US) | 2009-04-29 | — | — | CN | disclosed |