Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780715 | 0.90 | NOTUM (0.34) | NOTUMRORC | |
| SCHEMBL27765595 | 0.88 | HSD11B1 (0.40) | SLC6A9CA1CA2CA7CA9 | |
| SCHEMBL27765640 | 0.88 | NOTUM (0.42) | NOTUM | |
| SCHEMBL27744659 | 0.86 | SLC6A9 (0.41) | NOTUMSLC6A9RORCCA1CA2 | |
| SCHEMBL1470752 | 0.83 | NOTUM (0.41) | NOTUMSLC6A9TRPA1HDAC1CHRM2 | |
| SCHEMBL1470754 | 0.83 | NOTUM (0.41) | NOTUMSLC6A9TRPA1HDAC1CHRM2 | |
| SCHEMBL20309069 | 0.83 | NOTUM (0.41) | NOTUMSLC6A9TRPA1HDAC1CHRM2 | |
| SCHEMBL27744761 | 0.79 | F13A1 (0.34) | SLC6A9RORCCA1CA2CA7 | |
| SCHEMBL27765644 | 0.78 | — | — | |
| SCHEMBL27744766 | 0.77 | EGLN1 (0.34) | RORCMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421258-B | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYPSYS INC | 2013-08-21 | — | — | CN | disclosed |
| CN-101421258-A | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYSPSYS INC (US) | 2009-04-29 | — | — | CN | disclosed |