Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL8418695 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4LMNAMEN1 | |
| Acrylic Acid SCHEMBL15464233 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4LMNAMEN1 | |
| Acrylic Acid SCHEMBL8499374 | 0.91 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNAMEN1 | |
| Acrylic Acid SCHEMBL8500826 | 0.91 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNAMEN1 | |
| Acrylic Acid SCHEMBL1461885 | 0.88 | TSHR (0.69) | ALDH1A1TSHRFGFR4LMNALDHA | |
| Acrylamide SCHEMBL27880336 | 0.88 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNAMEN1 | |
| Acrylic Acid SCHEMBL26086 | 0.88 | ALDH1A1 (0.79) | ALDH1A1TSHRFGFR4LMNALDHA | |
| Acrylic Acid SCHEMBL9769250 | 0.88 | LMNA (0.71) | ALDH1A1TSHRFGFR4LMNAMEN1 | |
| Acrylic Acid SCHEMBL10675286 | 0.88 | ALDH1A1 (0.79) | ALDH1A1TSHRFGFR4LMNALDHA | |
| Acrylic Acid SCHEMBL7140121 | 0.88 | ALDH1A1 (0.79) | ALDH1A1TSHRFGFR4LMNALDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102117029-B | Decolorable toner, image forming device and image forming method | TOSHIBA TEC KK | 2013-09-11 | — | — | CN | disclosed |
| CN-102445870-B | Electrophotographic toner and method for producing the same | TOSHIBA TEC KK | 2013-08-07 | — | — | CN | disclosed |
| CN-102117029-A | Decolorable toner, image forming device and image forming method | TOSHIBA TEC KK | 2011-07-06 | — | — | CN | disclosed |
| CN-100444015-C | Liquid for electrophoretic display, display medium using the same, and display device | MITSUBISHI PENCIL CO (JP) | 2008-12-17 | — | — | CN | disclosed |