Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765794 | 0.86 | AOC3 (0.40) | XDHMAPTALDH1A1USP2CYP1A2 | |
| SCHEMBL4165895 | 0.84 | XDH (0.38) | XDHMAPTMCHR1GRM1 | |
| SCHEMBL27744844 | 0.83 | MAPT (0.51) | MAPTALDH1A1TSHRGRM1KMT2A | |
| SCHEMBL4164283 | 0.83 | GRM1 (0.47) | XDHMAPTMCHR1GRM1PTGS2 | |
| SCHEMBL4158635 | 0.82 | XDH (0.38) | XDHMAPTMCHR1GRM1TP53 | |
| SCHEMBL4168810 | 0.82 | GRM1 (0.41) | XDHMAPTMCHR1GRM1TP53 | |
| SCHEMBL4161595 | 0.80 | TDP2 (0.42) | XDHMAPTMCHR1GRM1PTGS2 | |
| SCHEMBL1753599 | 0.76 | XDH (0.42) | XDHMAPTALDH1A1USP2CYP1A2 | |
| SCHEMBL1689332 | 0.75 | GRM1 (0.48) | XDHMAPTALDH1A1USP2CYP1A2 | |
| SCHEMBL1689013 | 0.75 | GRM1 (0.50) | XDHMAPTALDH1A1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | claimed |
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | disclosed |