Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910111 | 0.87 | HTR7 (0.42) | CD274TAAR1CSNK2A1PNMT | |
| SCHEMBL28018977 | 0.85 | HTR7 (0.41) | CD274TAAR1CSNK2A1PNMT | |
| SCHEMBL27500689 | 0.85 | KDR (0.38) | — | |
| SCHEMBL20597604 | 0.84 | BRD4 (0.39) | CD274MAOBPDCD1 | |
| SCHEMBL27909907 | 0.83 | HTR7 (0.40) | CD274TAAR1CSNK2A1PNMT | |
| SCHEMBL3154256 | 0.82 | PDCD1 (0.38) | CD274CYP2A6PDCD1 | |
| SCHEMBL26668569 | 0.81 | HTR1A (0.31) | — | |
| SCHEMBL20599017 | 0.80 | — | — | |
| SCHEMBL20892241 | 0.78 | KCNH2 (0.31) | — | |
| SCHEMBL30065602 | 0.78 | PTAFR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101318887-B | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND | 2011-03-23 | — | — | CN | disclosed |
| CN-101318887-A | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND (CN) | 2008-12-10 | — | — | CN | disclosed |