SCHEMBL3154256

SCHEMBL3154256

CC1=Cc2cccc(-c3ccccc3)c2C1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
PRCP P42785 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP11 Q9NR21 1/20 0.38
CYP2A6 P11509 1/20 0.38
HTR1A P08908 2/20 0.36
HTR7 P34969 2/20 0.36
ANPEP P15144 2/20 0.36
IL1RN P18510 1/20 0.36
ERAP2 Q6P179 1/20 0.36
ERAP1 Q9NZ08 1/20 0.36
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HPGD P15428 1/20 0.33
BCL2L1 Q07817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16393922 0.93 PDCD1 (0.36) PDCD1CD274PRCPPARP10PARP11
SCHEMBL27500689 0.89 KDR (0.38)
SCHEMBL27171025 0.83 PRCP (0.33) PDCD1CD274PRCPHTR1AHTR7
SCHEMBL20165781 0.82 BRD9 (0.35) HTR1A
SCHEMBL26668569 0.82 HTR1A (0.31) PRCPHTR1AHTR7
SCHEMBL27744867 0.82 CD274 (0.43) PDCD1CD274CYP2A6
SCHEMBL5553099 0.82 PTAFR (0.39) ALDH1A1
SCHEMBL30065602 0.82 PTAFR (0.39) ALDH1A1
SCHEMBL29776193 0.81 BRD4 (0.35) PARP10PARP11HTR7ALDH1A1
SCHEMBL3150842 0.80 GSTP1 (0.42) CYP2A6ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102964371-B A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2015-08-12 CN claimed
CN-102964371-A Preparation method of silicon-bridged sterically-hindered cyclopentadiene compound SHANGHAI RES INST CHEMICAL IND 2013-03-13 CN claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US claimed
JP-7224079-A None JP disclosed
EP-4700052-A1 HYBRID SUPPORTED METALLOCENE CATALYST AND METHOD FOR PREPARING POLYETHYLENE USING SAME LG Chem, Ltd. (KR) 2026-02-25 EP disclosed
US-20250333549-A1 Process for Preparing a Catalyst for Olefin Polymerization HANWHA SOLUTIONS CORP (KR) 2025-10-30 US disclosed
US-12454588-B2 Powder type polypropylene resin and method for preparing the same LG CHEM, LTD. (KR) 2025-10-28 US disclosed
EP-3875496-B1 METHOD FOR PREPARING CATALYST FOR OLEFIN POLYMERIZATION HANWHA SOLUTIONS CORP (KR) 2025-09-03 EP disclosed
US-12384859-B2 Process for preparing a catalyst for olefin polymerization Hanwha Solutions Corporation (KR) 2025-08-12 US disclosed
US-12384860-B2 Hybrid supported metallocene catalyst and process for preparing polyethylene copolymer using the same LG CHEM, LTD. (KR) 2025-08-12 US disclosed
WO-2025037747-A1 METHOD FOR SOLUTION POLYMERIZATION OF ETHYLENE-ALPHA-OLEFIN COPOLYMER USING TRANSITION METAL COMPOUND 한화솔루션 주식회사 2025-02-20 WO disclosed
EP-0705281-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC. (US) 1996-04-10 EP disclosed
CN-1107162-A Metallocen method for preparation of same and application of same as catalyst HOECHST AG (DE) 1995-08-23 CN disclosed
JP-H07224079-A METALLOCENE COMPOUND HOECHST AG 1995-08-22 JP disclosed
EP-0659756-A1 Metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-28 EP disclosed
EP-0659757-A1 Metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-28 EP disclosed
EP-0654476-A1 Metallocenes, their preparation and use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-24 EP disclosed
WO-1994028034-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC. (US) 1994-12-08 WO disclosed
EP-0576970-A1 Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed