Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | COMT | P21964 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | METAP1 | P53582 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074924 | 0.77 | TSHR (0.42) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL2008753 | 0.74 | KDM4E (0.39) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL3886362 | 0.74 | MMP2 (0.34) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL10841983 | 0.74 | MEN1 (0.39) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL19001485 | 0.74 | MMP2 (0.34) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL1765856 | 0.74 | CYP3A4 (0.39) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL12737722 | 0.74 | BACE1 (0.48) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL19055257 | 0.74 | PSMD14 (0.57) | METAP2TSHRMMP2CHRM1COMT | |
| SCHEMBL3887261 | 0.74 | LMNA (0.38) | METAP2TSHRMMP2ADRA1AKDM4E | |
| SCHEMBL277448 | 0.74 | KDM4E (0.34) | METAP2TSHRMMP2CHRM1COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493956-B1 | MOISTURE-CURING FORMULATIONS WITH TIME-MODIFIED CURING BEHAVIOR | HENKEL AG & CO KGAA (DE) | 2018-04-18 | — | — | EP | claimed |
| US-9428529-B2 | Process for purification of trivalent phosphorous ligands that can be used for preparation of catalysts | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2016-08-30 | — | — | US | claimed |
| CN-102712751-B | Moisture-curing formulations with time-modified phases | HENKEL AG & CO KGAA | 2015-06-10 | — | — | CN | claimed |
| US-8592517-B2 | Moisture-curing formulations with time-modified phases | HENKEL AG & CO. KGAA (DE) | 2013-11-26 | — | — | US | claimed |
| US-20120277373-A1 | MOISTURE-CURING FORMULATIONS WITH TIME-MODIFIED PHASES | HENKEL AG & CO. KGAA (DE) | 2012-11-01 | — | — | US | claimed |
| EP-1558585-A4 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LTD (AU) | 2008-07-02 | — | — | EP | claimed |
| CN-1720238-A | Neurologically-active compounds | PRANA BIOTECHNOLOGY LTD (AU) | 2006-01-11 | — | — | CN | claimed |
| EP-1558585-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | Prana Biotechnology Ltd (AU) | 2005-08-03 | — | — | EP | claimed |
| WO-2004031161-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2004-04-15 | — | — | WO | claimed |
| US-5385990-A | Blend of epoxy compound, amine hardener and hydroxy substituted aromatic compound | LORD CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| EP-0596622-A2 | Epoxy resin structural adhesive composition having high temperature resistance | LORD CORPORATION (US) | 1994-05-11 | — | — | EP | claimed |
| EP-0377357-B1 | Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst | INST FRANCAIS DU PETROLE (FR) | 1994-03-23 | — | — | EP | claimed |
| US-20200339598-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2020-10-29 | — | — | US | disclosed |
| CN-106009788-B | Coating liquid for forming coating film, method for producing same, and method for producing substrate with coating film | 日挥触媒化成株式会社 | 2020-06-16 | — | — | CN | disclosed |
| CN-106497400-B | Coating liquid for forming coating film, method for producing coating liquid for forming coating film, and substrate with coating film | 日挥触媒化成株式会社 | 2020-04-03 | — | — | CN | disclosed |
| EP-2607416-B1 | THERMOPLASTIC RESIN FOAM, METHOD OF PRODUCING THE SAME, AND LIGHT REFLECTING MATERIAL USING THE SAME | FURUKAWA ELECTRIC CO LTD (JP) | 2019-10-02 | — | — | EP | disclosed |
| EP-0671397-A1 | Alkylaminoindanes compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-5385990-A | Blend of epoxy compound, amine hardener and hydroxy substituted aromatic compound | LORD CORPORATION (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0596622-A2 | Epoxy resin structural adhesive composition having high temperature resistance | LORD CORPORATION (US) | 1994-05-11 | — | — | EP | disclosed |
| US-4143075-A | RHODIUM-CARBON MONOXIDE-TRIARYLPHOSPHINE CATALYST, SEQUESTERING IRON SALT CONTAMINANTS | UNION CARBIDE CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339598-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | NR4A1, NCOA4, NR4A2 | METAP2 3811/4885TSHR 2821/4885MMP2 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.