Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 9/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764932 | 0.84 | MLYCD (0.63) | MLYCDBRD4TDO2 | |
| SCHEMBL10502800 | 0.83 | MLYCD (0.66) | MLYCDMAPK14BRD4MAPK9MAPK10 | |
| SCHEMBL10503592 | 0.81 | MLYCD (0.64) | MLYCDMAPK14BRD4TDO2 | |
| SCHEMBL10503952 | 0.81 | MLYCD (0.64) | MLYCDMAPK14BRD4TDO2 | |
| SCHEMBL10505666 | 0.78 | MLYCD (0.59) | MLYCDRAB9A | |
| SCHEMBL4874434 | 0.76 | MLYCD (1.00) | MLYCD | |
| SCHEMBL4327769 | 0.72 | BRD4 (0.60) | MLYCDMAPK14KIF11BRD4MAPK9 | |
| SCHEMBL4339786 | 0.71 | MAPK14 (0.63) | MLYCDMAPK14MAPK9MAPK10MAPK11 | |
| SCHEMBL8764291 | 0.71 | BRD4 (0.53) | MLYCDBRD4TDO2 | |
| SCHEMBL10731646 | 0.71 | MLYCD (0.52) | MLYCDBRD4NPC1RAB9ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472921-B | Pyridylisoxazole derivative | ASKA PHARM CO LTD | 2012-10-10 | — | — | CN | disclosed |
| CN-101472921-A | Pyridylisoxazole derivative | ASKA PHARM CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |