Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 13/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764932 | 0.86 | MLYCD (0.63) | BRD4TDO2MLYCDPTGS1POLB | |
| SCHEMBL8765096 | 0.73 | L3MBTL1 (0.45) | BRD4TDO2MLYCDPTGS1POLB | |
| SCHEMBL27744909 | 0.71 | MLYCD (0.61) | BRD4TDO2MLYCD | |
| SCHEMBL10502800 | 0.71 | MLYCD (0.66) | BRD4TDO2MLYCD | |
| SCHEMBL10503952 | 0.70 | MLYCD (0.64) | BRD4TDO2MLYCDPTGS1NOTUM | |
| SCHEMBL544899 | 0.69 | BRD4 (1.00) | BRD4TDO2MLYCDPTGS1NOTUM | |
| SCHEMBL4420017 | 0.69 | MLYCD (1.00) | MLYCDESR1ESR2 | |
| SCHEMBL4874434 | 0.69 | MLYCD (1.00) | MLYCD | |
| SCHEMBL8765219 | 0.67 | MLYCD (0.35) | BRD4MLYCD | |
| SCHEMBL10505666 | 0.67 | MLYCD (0.59) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797492-A | INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1989-01-10 | — | — | US | claimed |
| EP-0220947-A2 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | claimed |
| EP-0375670-B1 | Process for preparing 3-polyfluoroalkylisoxazolylamines | SHIONOGI & CO (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0220947-B1 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0375670-A2 | Process for preparing 3-polyfluoroalkylisoxazolylamines | SHIONOGI & CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |
| US-4797492-A | INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0220947-A2 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |