Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 7/20 | 0.63 |
| ▸ | BRD4 | O60885 | 3/20 | 0.56 |
| ▸ | TDO2 | P48775 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764291 | 0.86 | BRD4 (0.53) | MLYCDBRD4TDO2POLBPTGS1 | |
| SCHEMBL10502800 | 0.84 | MLYCD (0.66) | MLYCDBRD4TDO2ENPP1PTGS2 | |
| SCHEMBL10503592 | 0.83 | MLYCD (0.64) | MLYCDBRD4TDO2ENPP1 | |
| SCHEMBL10503952 | 0.83 | MLYCD (0.64) | MLYCDBRD4TDO2PTGS1NOTUM | |
| SCHEMBL10505666 | 0.79 | MLYCD (0.59) | MLYCDENPP1PTGS2 | |
| SCHEMBL9674379 | 0.79 | PTGS1 (0.46) | MLYCDBRD4TDO2POLBPTGS1 | |
| SCHEMBL4874434 | 0.78 | MLYCD (1.00) | MLYCD | |
| SCHEMBL8764336 | 0.75 | TDO2 (0.46) | MLYCDBRD4TDO2POLBPTGS1 | |
| SCHEMBL10502923 | 0.72 | MLYCD (0.52) | MLYCDBRD4 | |
| SCHEMBL10731646 | 0.72 | MLYCD (0.52) | MLYCDBRD4POLBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797492-A | INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1989-01-10 | — | — | US | claimed |
| EP-0220947-A2 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | claimed |
| EP-0375670-B1 | Process for preparing 3-polyfluoroalkylisoxazolylamines | SHIONOGI & CO (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0220947-B1 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0271975-B1 | 3-PERFLUOROALKYL-ISOXAZOL-5-YL-OXYCARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-06-24 | — | — | EP | disclosed |
| EP-0375670-A2 | Process for preparing 3-polyfluoroalkylisoxazolylamines | SHIONOGI & CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |
| US-4888044-A | PREEMERGENCE HERBICIDES | SHIONOGI & CO., LTD. (JP) | 1989-12-19 | — | — | US | disclosed |
| US-4797492-A | INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0271975-A1 | 3-Perfluoroalkyl-isoxazol-5-yl-oxycarboxylic acid derivatives, processes for their preparation and their use as herbicides | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0220947-A2 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |