SCHEMBL2774493

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9610531	0.92	ELANE (0.39)	ELANEALDH1A1MAPTKMT2AMEN1
	SCHEMBL19718972	0.90	PDK2 (0.41)	PDK2
	SCHEMBL9610460	0.89	HSD17B10 (0.35)	ELANETHRBTDP1ALDH1A1MAPT
	SCHEMBL9610306	0.89	ELANE (0.38)	ELANEALDH1A1MAPTPDK2KMT2A
	SCHEMBL9610489	0.83	ELANE (0.40)	ELANEALDH1A1MAPTNOTUM
	SCHEMBL996855	0.83	THRB (0.43)	ELANETHRBTDP1ALDH1A1MAPT
	SCHEMBL9610307	0.82	MAPT (0.38)	ELANEALDH1A1MAPTKMT2AMEN1
	SCHEMBL9610310	0.82	GSK3B (0.36)	ELANEALDH1A1MAPTKMT2AMEN1
	SCHEMBL9610546	0.82	ELANE (0.39)	ELANEALDH1A1MAPTKMT2AMEN1
	SCHEMBL9610553	0.82	ELANE (0.39)	ELANETDP1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.