Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775517 | 0.85 | P2RY12 (0.40) | CCR1KCNH2KMT2AP2RY12 | |
| Hydrochloric Acid SCHEMBL2777276 | 0.84 | GPR119 (0.39) | GPR119KCNH2L3MBTL1ERBB2KMT2A | |
| SCHEMBL2775840 | 0.83 | CCR1 (0.45) | CCR1GPR119KCNH2TSHRKMT2A | |
| SCHEMBL6524429 | 0.81 | RBP4 (0.37) | GPR119KCNH2L3MBTL1ERBB2 | |
| SCHEMBL2776203 | 0.79 | CCR1 (0.49) | CCR1TSHRKMT2A | |
| SCHEMBL2774697 | 0.79 | CCR1 (0.49) | CCR1KCNH2 | |
| SCHEMBL3712937 | 0.79 | GPR119 (0.47) | GPR119L3MBTL1KMT2A | |
| SCHEMBL2775696 | 0.78 | EPHX2 (0.53) | CCR1GPR119KCNH2TSHRKMT2A | |
| SCHEMBL2774377 | 0.77 | GPR119 (0.52) | GPR119 | |
| SCHEMBL2776919 | 0.76 | CCR1 (0.48) | CCR1KCNH2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |