Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720714 | 0.89 | GPR119 (0.47) | GPR119TLR9TLR8TLR7HRH1 | |
| SCHEMBL3717758 | 0.83 | TLR9 (0.47) | GPR119TLR9TLR8TLR7JAK2 | |
| SCHEMBL2774377 | 0.83 | GPR119 (0.52) | GPR119 | |
| SCHEMBL3708950 | 0.83 | GPR119 (0.45) | GPR119HRH1 | |
| Hydrochloric Acid SCHEMBL2777276 | 0.81 | GPR119 (0.39) | GPR119HRH3CYP2C9SLC6A15KDM4E | |
| SCHEMBL3648875 | 0.80 | HRH1 (0.46) | GPR119HRH1SLC6A15 | |
| SCHEMBL3709889 | 0.79 | GPR119 (0.45) | GPR119TLR9TLR8TLR7HRH1 | |
| SCHEMBL2774529 | 0.79 | CCR1 (0.41) | GPR119KMT2AL3MBTL1 | |
| SCHEMBL3651433 | 0.78 | HRH1 (0.44) | GPR119HRH1 | |
| SCHEMBL3711292 | 0.77 | HRH1 (0.51) | CYP2C9HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |