Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28773310 | 0.99 | PDK2 (0.33) | PDK2MEN1APAF1NPC1POLB | |
| SCHEMBL2160591 | 0.81 | METAP2 (0.41) | MEN1NPC1POLBKMT2ATSHR | |
| SCHEMBL29034386 | 0.78 | DCUN1D1 (0.45) | NPC1ABCG2AKT1AKT2DCUN1D2 | |
| SCHEMBL3397570 | 0.78 | DCUN1D1 (0.47) | NPC1ABCG2AKT1AKT2DCUN1D2 | |
| SCHEMBL29499607 | 0.78 | DCUN1D1 (0.47) | NPC1ABCG2AKT1AKT2DCUN1D2 | |
| SCHEMBL9539905 | 0.78 | DCUN1D1 (0.33) | AKT1AKT2DCUN1D2DCUN1D1 | |
| SCHEMBL12017490 | 0.77 | BTK (0.41) | MEN1POLBKMT2ATSHRNTRK1 | |
| SCHEMBL9709791 | 0.76 | LMNA (0.48) | NPC1POLBKMT2AABCB1ABCG2 | |
| SCHEMBL1774163 | 0.75 | FOLH1 (0.37) | PDK2TSHRTDP1 | |
| SCHEMBL1463312 | 0.75 | KDR (0.48) | MEN1NPC1KMT2APIM1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268065-A | Process for preparing an angiotensin II receptor antagonist | FARMAPROJECTS S L (ES) | 2008-09-17 | — | — | CN | claimed |
| CN-101268065-A | Process for preparing an angiotensin II receptor antagonist | FARMAPROJECTS S L (ES) | 2008-09-17 | — | — | CN | disclosed |