Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27166398 | 0.98 | TDP1 (0.58) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL8332454 | 0.95 | CHRM2 (0.56) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL9207150 | 0.87 | GLS (0.55) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL16882232 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL28449486 | 0.85 | TDP1 (0.59) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL4581242 | 0.85 | TDP1 (0.59) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL6790333 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL1162143 | 0.84 | TDP1 (0.57) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8862878 | 0.82 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL2604742 | 0.82 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432268-B | 4- (2-amino-1-hydroxyethyl) phenol derivatives as beta 2 adrenoreceptor agonists | ALMIRALL LAB | 2011-02-16 | — | — | CN | disclosed |
| CN-101432268-A | 4- (2-amino-1-hydroxyethyl) phenol derivatives as beta 2 adrenoreceptor agonists | ALMIRALL LAB (ES) | 2009-05-13 | — | — | CN | disclosed |