Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826414 | 0.85 | ALDH1A1 (0.49) | RECQLEPHX2NPC1RAB9AKMT2A | |
| SCHEMBL28822397 | 0.82 | PTPN1 (0.55) | EPHX2RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2955532 | 0.82 | CA12 (0.70) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL13200773 | 0.80 | RECQL (0.73) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL1425366 | 0.79 | EPHX2 (0.71) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL11417263 | 0.78 | RAB9A (0.84) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL1425023 | 0.78 | EPHX2 (0.74) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL3960592 | 0.77 | EPHX2 (0.72) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL3958860 | 0.76 | EPHX2 (0.76) | RECQLEPHX2EPHX1NPC1RAB9A | |
| SCHEMBL19107725 | 0.76 | SMN1; SMN2 (0.70) | RECQLEPHX2EPHX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326166-A | Novel N-sulfamoyl-piperidine amides for the prevention or treatment of obesity and related disorders | SOLVAY PHARM GMBH (DE) | 2008-12-17 | — | — | CN | disclosed |