Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033000 | 0.87 | L3MBTL1 (0.60) | PTPN1PTPN2PTPN6MAPTFAAH | |
| SCHEMBL28092176 | 0.87 | GLA (0.58) | PTPN1PTPN2PTPN6MAPTFAAH | |
| SCHEMBL28033418 | 0.86 | HTT (0.62) | PTPN1PTPN2PTPN6MAPTEPHX2 | |
| SCHEMBL28282732 | 0.84 | TP53 (0.64) | HTTKMT2ARXFP1SMN1; SMN2TSHR | |
| SCHEMBL28264102 | 0.84 | PTPN1 (0.52) | PTPN1PTPN2PTPN6MAPTLMNA | |
| SCHEMBL28033057 | 0.83 | ACHE (0.53) | PTPN1PTPN2PTPN6MAPTKMT2A | |
| SCHEMBL27745908 | 0.82 | RECQL (0.62) | EPHX2KMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL28455754 | 0.82 | PTPN1 (0.81) | PTPN1PTPN2PTPN6MAPTFAAH | |
| SCHEMBL27826414 | 0.82 | ALDH1A1 (0.49) | MAPTEPHX2HTTKMT2ARAB9A | |
| SCHEMBL27710057 | 0.81 | TP53 (0.55) | MAPTEPHX2LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-A | Tripeptide epoxy ketone compound constructed by heterocycle as well as preparation method and application thereof | UNIV ZHEJIANG | 2015-09-30 | — | — | CN | disclosed |