Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938830 | 0.84 | TGM2 (0.50) | MAPTKDM4EPKMALDH1A1HPGD | |
| SCHEMBL27523895 | 0.81 | ALDH1A1 (0.57) | MAPTKDM4EPKMALDH1A1HPGD | |
| SCHEMBL27523893 | 0.81 | KDM4E (0.63) | MAPTKDM4EPKMALDH1A1HPGD | |
| SCHEMBL27698379 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDHTTGAA | |
| SCHEMBL27792212 | 0.75 | HPGD (0.54) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27483868 | 0.75 | GAA (0.50) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL27905665 | 0.75 | HTT (0.51) | MAPTKDM4EPKMALDH1A1HPGD | |
| SCHEMBL29907228 | 0.74 | KDM4E (0.48) | MAPTKDM4EPKMALDH1A1HPGD | |
| SCHEMBL3635005 | 0.73 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDLMNAHTT | |
| SCHEMBL27666297 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489989-A | Pentadiene amide derivative | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |