SCHEMBL3635005

SCHEMBL3635005

NCc1ccccc1NC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
MAPT P10636 4/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
POLB P06746 2/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27483868 0.86 GAA (0.50) ALDH1A1MAPTGAAHPGDL3MBTL1
SCHEMBL27905665 0.86 HTT (0.51) ALDH1A1MAPTGAAHPGDL3MBTL1
SCHEMBL27666297 0.84 ALDH1A1 (0.43) ALDH1A1MAPTGAAHPGDL3MBTL1
SCHEMBL948318 0.83 MAPT (0.59) ALDH1A1MAPTGAAHPGDL3MBTL1
SCHEMBL4622869 0.83 L3MBTL1 (0.56) ALDH1A1MAPTGAAHPGDL3MBTL1
SCHEMBL7511265 0.83 HDAC3 (0.61) MAPTHPGDPOLBHDAC3HDAC1
SCHEMBL27698379 0.82 ALDH1A1 (0.42) ALDH1A1MAPTGAAHPGDL3MBTL1
SCHEMBL8631475 0.82 ALDH1A1 (0.55) ALDH1A1MAPTGAAHPGDPOLB
SCHEMBL17976487 0.82 TP53 (0.59) MAPTGAAPOLBHTTLMNA
Hydrochloric Acid SCHEMBL22346017 0.82 MAPT (0.58) ALDH1A1MAPTGAAHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116422151-B Application method of slime stripping agent for reverse osmosis membrane system 杭州尚善若水环保科技有限公司 2023-09-26 CN disclosed
CN-116422151-A Application method of slime stripping agent for reverse osmosis membrane system 杭州尚善若水环保科技有限公司 2023-07-14 CN disclosed
WO-2019186260-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HIKAL LIMITED (IN) 2019-10-03 WO disclosed
CN-104151292-A Indole derivative or pharmaceutically acceptable salt thereof KISSEI PHARMACEUTICAL 2014-11-19 CN disclosed
EP-2788359-A1 COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS Research Triangle Institute (US) 2014-10-15 EP disclosed
WO-2013086200-A1 COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS RESEARCH TRIANGLE INSTITUTE (US) 2013-06-13 WO disclosed
CN-102498097-A Indole derivatives or pharmaceutically acceptable salts thereof KISSEI PHARMACEUTICAL 2012-06-13 CN disclosed
EP-2150553-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES Abbott Laboratories (US) 2010-02-10 EP disclosed
WO-2008141145-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (US) 2008-11-20 WO disclosed
WO-2008141140-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (US) 2008-11-20 WO disclosed
EP-1968979-A2 9-MEMBERED HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (US) 2008-09-17 EP disclosed
WO-2007067781-A2 9-MEMBERED HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PROTEIN KINASES ABBOTT LABORATORIES (US) 2007-06-14 WO disclosed