Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780954 | 0.99 | PTPN11 (0.50) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL5184493 | 0.82 | FTO (0.56) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL29459575 | 0.82 | FTO (0.56) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL5184495 | 0.82 | FTO (0.56) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL11608216 | 0.80 | ALDH3A1 (0.47) | PTPN11CA12CA9CA2MEN1 | |
| SCHEMBL24213305 | 0.79 | NPC1 (0.59) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL5838349 | 0.79 | NPC1 (0.59) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL5838346 | 0.79 | NPC1 (0.59) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL11606940 | 0.79 | PTPN11 (0.48) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 | |
| SCHEMBL11612113 | 0.79 | L3MBTL1 (0.56) | PTPN11SMN1; SMN2PTPN1PTPN6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472744-B | Reversibly thermochromic system, composition, article and method for reversibly thermochromic coloring a carrier material | CIBA HOLDING INC | 2011-09-14 | — | — | CN | disclosed |
| CN-101472744-A | Reversible thermochromic compositions | CIBA HOLDING INC (CH) | 2009-07-01 | — | — | CN | disclosed |