Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | IL1B | P01584 | 2/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29073375 | 0.81 | CDK5 (0.38) | BRD4AADATCREBBPKDM4EALDH1A1 | |
| SCHEMBL4067227 | 0.81 | AADAT (0.49) | BRD4DDB1CRBNAADATCREBBP | |
| SCHEMBL1450613 | 0.81 | PARP1 (0.36) | PARP1BRD4TNFIL1BIKZF1 | |
| SCHEMBL13725343 | 0.81 | AADAT (0.49) | PARP1BRD4DDB1CRBNAADAT | |
| Hydrochloric Acid SCHEMBL25331216 | 0.80 | CDK5 (0.37) | BRD4AADATCREBBPKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30576552 | 0.80 | CDK5 (0.37) | BRD4AADATCREBBPKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4894658 | 0.80 | AADAT (0.48) | PARP1BRD4DDB1CRBNAADAT | |
| SCHEMBL4795933 | 0.78 | AADAT (0.52) | BRD4AADATCREBBPALDH1A1MAPT | |
| SCHEMBL3593980 | 0.78 | HTR5A (0.35) | PARP1BRD4TNFIL1BIKZF1 | |
| SCHEMBL3591908 | 0.78 | CREBBP (0.38) | PARP1BRD4TNFIL1BIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489989-A | Pentadiene amide derivative | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |