Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595541 | 0.84 | HSP90AA1 (0.35) | HTR5ABRD4CREBBPDDB1CRBN | |
| SCHEMBL3598950 | 0.84 | ALDH1A1 (0.34) | HTR5ABRD4DDB1CRBNTNF | |
| SCHEMBL3593976 | 0.83 | CREBBP (0.34) | BRD4CREBBPDDB1CRBNPARP1 | |
| SCHEMBL3592386 | 0.83 | TRPV1 (0.38) | HTR5ACREBBPDDB1CRBNHTR1A | |
| SCHEMBL3584557 | 0.83 | DDB1 (0.37) | HTR5ABRD4CREBBPDDB1CRBN | |
| SCHEMBL3590436 | 0.81 | TRPV1 (0.40) | DDB1CRBNHTR1AHTR2AOPRM1 | |
| SCHEMBL27746212 | 0.78 | PARP1 (0.37) | HTR5ABRD4CREBBPDDB1CRBN | |
| SCHEMBL7484149 | 0.77 | DDB1 (0.33) | HTR5ABRD4CREBBPDDB1CRBN | |
| SCHEMBL1450613 | 0.76 | PARP1 (0.36) | HTR5ABRD4CREBBPDDB1CRBN | |
| SCHEMBL3596677 | 0.76 | CRBN (0.33) | HTR5ABRD4CREBBPDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | HTR5A 2037/4885BRD4 706/4885CREBBP 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.